Bowel Endotoxin

00:00 Well, welcome to this month’s Ask Your Herb Doctor. My name’s Andrew Murray. My name’s Sarah Johanneson Murray. For those of you who perhaps have never listened to our shows which run every third Friday of the month from 7 to 8pm, we’re both licensed medical herbalists who trained in England and graduated there with a degree in herbal medicine. We run a clinic in Garberville where we consult with clients about a wide range of conditions and we manufacture all our own certified organic herbal extracts, which are either grown on our CCF certified herb farm or which are sourced from other USA certified organic suppliers. So you’re listening to Ask Your Herb Doctor on KMUD Garberville 91.1 FM. And from 7.30 until the end of the show at 8 o’clock, you’re invited to call in with any questions either related or unrelated to this month’s topic of bowel endotoxin. So the number here if you live in the area is 923-3911. 01:02 Or if you live outside the area, the toll-free number is 1-800-KMUD-RAD. And we can also be reached toll-free on 1-888-WBM-URB for further questions during normal business hours Monday through Friday. So this month we’re again very pleased and fortunate to welcome Dr. Ray Pete back to this show and we’ll be exploring the emerging revelation concerning endotoxemia and how unsaturated fats further burden our bodies in ways we could never imagine. So welcome to tonight’s show Dr. Pete. Thanks. Okay, perhaps for those people that are tuning in this evening, if you could outline what is endotoxin, how is it formed and how is it harmful to our health? I’m not sure that people really know what it’s doing in the bacterium, but it’s been known since 1892. 02:05 It was called endotoxin to distinguish it from the older known bacterial toxins that the bacteria in effect secrete to poison something in their environment. Supposedly the endotoxin only comes out when the bacterium is broken apart, but I think actually it leaks a little bit all the time. So I wouldn’t say that it’s strictly an endotoxin like the textbooks used to say, but it’s somewhat of a structural protein, but it’s a medium to smallish molecule that can leak out in the process of growth and salivation and so on. And its other name is lipopolysaccharide because its structure is a chain of sugar molecules 03:08 with fatty acids attached. And that gives it kind of a soap-like behavior that is part of why it’s toxic so generally. And they are so common in the environment that organisms have their basic defenses against them. Their basic defenses is the high-density lipoprotein. And they talk about it in terms of carrying cholesterol, but I think really it’s a historic main function is that it’s our first defense against endotoxin once the endotoxin gets into the bloodstream, but normally the intestine is a good barrier against absorbing the endotoxins. 04:15 And if some of it leaks through the wall of the intestine into the blood vessels and gets carried to the liver, the liver enzymes break it down and so it shouldn’t normally reach the bloodstream in significant amounts, but it’s a matter of tens of milligrams that can circulate into the bloodstream every day. Do you know as an aside, do you know if there is a value, a pigger gram or whatever, a value associated to a quote acceptable level of… Yeah, it stimulates defense reactions and so it’s kind of like a toughening up reaction to have a small amount of it. If you’re born in a germ-free environment, your first exposure to bacteria is likely to 05:19 be lethal, but absorbing a little bit of the endotoxin toughens up the system. Okay, this would be, and again, as an aside, it’s not something I was planning on going through with you, but perhaps this harkens back to the, as you said, the kind of germ, yeah, I’ll say germ-ridden, but the germ-prevalent society maybe of a hundred years ago producing children that had better immune systems and did not have autism or any of the other syndromes maybe associated with the sterile environments of today. Yeah, I think at the ups and downs when you try to be too sterile and then are exposed inevitably to germs, the sudden shock is probably a lot more stressful. Right. Okay, we’re getting back to endotoxins and you mentioned lipopolysaccharide and some 06:19 people will have heard of LPS or lipopolysaccharide. How is it harmful to our health if the bacteria, if I’m right in thinking that this bacteria are the main source of this endotoxin and we are exposed to varying amounts of it daily? How is it harmful to our health? It triggers a whole series of reactions and it seems to be a physical, chemical process that sort of stirs up a cell to recognize a threat and set off a chain of reactions. And it’s the things that it sets into action that really cause the chronic accumulating damage, degenerative damage. It’s one of the first things that does on exciting a cell is to cause the cell to take 07:30 up calcium and to activate the synthesis of nitric oxide and the nitric oxide and the cell excitation that goes with absorbing calcium trigger other reactions and a small amount of endotoxin can stimulate the intestine to contract more. But if the cells are getting overloaded with it, that and possibly other irritants can cause cells to produce so much nitric oxide that the nitric oxide becomes a major metabolic disrupter and will cause the intestine to lose the ability to contract and it will poison 08:31 the respiratory apparatus so that cells can’t make energy to fight back. And at that point with increased nitric oxide and reduced energy and taking up calcium, the cells also take up water. And then they become basically non-functioning to a degree? Yeah, they’re under stress and if the body can deliver enough energy to them quickly, they can excrete the water and the calcium and turn off the nitric oxide and return to normal functioning. But when they swell up, another place that the textbooks give a very simplified mistaken idea of what is involved in bowel damage from endotoxin. They talk about the leakage between cells as if the cells lose the glue that holds them 09:39 in contact with each other so holes open up between cells. That does happen but it isn’t necessarily the worst way that the endotoxin gets into the cells and passes through the cells. The whole structure of the cell, the cytoplasm, as it takes up water instead of being fat-like and tending to exclude water and prefer to absorb fats, the introduction of this sugar that is connected to a fat acts like a soap and makes the cell tend to admit not only more water but pretty much anything that is in its environment so the whole substance of the cell becomes kind of spongy and leaky and when this starts affecting the whole organism, 10:48 that kind of change occurs all through the body. Once the stuff has passed through the lining of the intestine and crosses across capillaries and gets into the bloodstream, then the endotoxin starts doing the same thing to any cell it comes to and so it will leak out of capillaries no matter where it is in the bloodstream if the liver hasn’t filtered it. So if it happens to reach the brain, it will cause the brain capillaries to leak whatever is in the bloodstream and so it can contribute to multiple sclerosis and the endotoxin leaking into the brain does the same thing. It triggers the release of nitric oxide and a whole chain of chemical reactions that every 11:54 organ has its particular way of responding to the endotoxin but there is a generality no matter what the organ. There are basic defense reactions that will occur not only to endotoxin but to any radical threat to the survival of the cell so that x-rays and gamma rays will produce essentially the same kind of change in brain cells or bowel cells that endotoxin does and so if you’re overexposed to x-rays for example you’ll get constipated the same way that overexposure to endotoxin will cause constipation. Okay so there’s a kind of saponification going on then. Yeah and opening up, loosening up of the cell structure so it becomes instead of like if 13:02 you imagine a lump of gelatin dipped, soaked in oil, it’ll stay stable in the presence of water but if you mix a little bit of lecithin with it, it’ll quickly start taking up water and then the whole thing is on the road to dissolving and breaking up. Okay, well perhaps this would leave me on to my next question for you which was that many of our listeners perhaps have heard the term leaky gut or leaky gut syndrome. Can you outline again, well perhaps you’ve already done that in part but can you outline what causes a leaky gut then and how a leaky bowel wall may lead to this translocation of bacteria and or endotoxin into the bloodstream? Yeah endotoxin is always present in the intestine and it’s always the first thing to defend 14:09 against but many other stresses and toxins like radiation or heavy metals or estrogenic substances or too many polyunsaturated fatty acids and so on. All of these things tend to loosen up or saponify the cell structure, cause the cell to take up water and let junk enter from the environment into the cell substance itself. And getting into the cell substance then it can just as easily go out the other side of the cell into the underlying extracellular material and from there across the capillary cells and into the bloodstream and that is essentially what the leaky gut is, it’s leaky 15:10 cell substance which involves leaky capillaries and ultimately it can cause leakiness of any tissue in the precancerous states for example you see substance leaking out of the characteristic cell and those indicate a tendency to develop cancer in that organ because that organ is most stressed and is leaking its substance. For example the prostate specific antigen is just a normal prostate protein that leaks out because the cell is under stress and the same protein leaks out of breast cells when they’re under stress and the characteristic proteins leak out of any cell when it’s under stress. So it literally is the cell is falling apart, it’s breaking down, it’s leaking. 16:17 And something as simple as vitamin E can tremendously strengthen the cell and help to hold it together so it doesn’t leak its protein substance out into the environment. And what would be the mechanism behind that? Well no one really knows but partly it’s stopping the free radical damage that nitric oxide is producing and it helps to keep calcium from overloading the cell and keeps the water from associating too closely with the proteins. And a lot of protective substances will do that. The natural hormones progesterone and testosterone help to toughen up the cell and keep it from leaking. The factors similar to vitamin E that are associated with energy production, coenzyme 17:24 Q10 and vitamin K are closely associated with vitamin E and energy production and they are extremely powerful at defending the respiratory apparatus from nitric oxide and endotoxin. When you mentioned a few moments ago when you’re talking about the influx of water into the cell and the cell not having sufficient energy, would thyroid be a part to play in raising the energy of the cell? Yeah, the thyroid is essential for making the enzyme that essentially allows oxygen to absorb electrons out of the mitochondrial system. The mitochondria takes up electrons from sugars and fats and drives energy from those 18:27 electrons as they’re passed along to oxygen and thyroid is the essential factor for making that happen and there are other supporting factors, a system called the uncoupling proteins that simply make the electrons run more quickly to be taken up by oxygen. What that does is produce carbon dioxide more quickly which turns off the formation of lactic acid and that turns off basically the nitric oxide forming system. If you can run the system fast enough with plenty of thyroid then you’ll make the carbon dioxide and inhibit lactic acid formation and pretty well defend against producing nitric 19:29 oxide and that gives you relative immunity to the lipopolysaccharide. Okay, is that what they call the electron transport chain, the NADH and that other cycle? The electrons pass from that down to oxygen but they can’t do it without thyroid and the temperature is one of the factors. When you run the electrons through this system you produce heat as well as carbon dioxide and ATP and keeping the temperature up is one of the things that helps to turn off the production of nitric oxide and other free radical destructive factors. So all of these harmful x-rays, LPS from the bacteria in our intestines, excess of estrogen 20:30 that our own bodies can just be producing not necessarily from what we’re taking as HRT or other forms of oral contraceptive pills but all of these things are essentially free radicals that are damaging our oxygen usage. Is that correct Dr. P? Yeah and not all free radicals are toxic but nitric oxide, the one that is so widely produced in response to stress, it increases greatly with aging too just because aging involves the progressive stress reactions. I remember the, I think they were called poppers, these weren’t these chemicals or drugs of some kind that were nitric oxide based and were becoming, and they were very damaging and that’s probably why, is to just explain the… Yeah nitric glycerin has been used as a drug to open the circulation of the heart and nitric 21:36 oxide didn’t really get much interest scientifically until Viagra came along and that’s basically doing the same thing as nitric glycerin but it’s extremely toxic, it’s like eating toxins and getting irradiated and getting old ahead of time. Wow, quite a price to pay. So it’s just a very potent, powerful free radical that people don’t really realize the damage that they’re creating by depleting their bodies of oxygen. Yeah and some free radicals can actually defend against the toxic free radicals. When the thyroid and oxygen are working properly, the electron transport chain involves lots 22:37 of free radical activity but it is all productive and protective. The faster you run oxygen through the mitochondrion under the influence of thyroid, the less free radical damage you have to the structure of the cell in the mitochondrion. If you are low thyroid or somehow lack oxygen acutely, the electrons instead of being safely pass through this chain of free radicals, the free radicals wander off and attack the fats that make up the mitochondrion and then those fats become peroxides which are sort of a randomly destructive kind of free radical. 23:37 So these would be the polyunsaturated fats that you’re talking about which just for our listeners to clarify includes the common vegetable oils available like corn oil, sunflower seed oil, canola, fish oil, hemp seed oil, flak seed oil, cotton seed oils and a lot of pre-processed packaged foods. And all of those tend to accumulate in the tissues and when they’re given acutely as an emulsion for example they used to do it in hospitals to fatten people up, now they do it to suppress their immune systems if they’re transplanting a kidney but they not only suppress immunity, they create sort of an instantaneous diabetes or inability to respire and use sugar. So it’s like if we eat food that’s fried in these oils and we’re essentially ingesting 24:39 a free radical? Very quickly and an experiment I did illustrates how even at room temperature they spontaneously oxidize. I put a rubber hose in a bottle of I think it was safflower oil and put the other end in a glass of water and just at room temperature over a few hours the bottle was in effect respiring. It was sucking oxygen up and drawing water up into the tube. The oxygen was combining with the unsaturated fats and in the process forming lipid peroxides which are toxic free radicals. And the situation is even worse in our body when it’s at 98 and above degrees. 25:39 Yeah much faster at that temperature and we have catalytic amounts of iron and heavy metals floating around to accelerate the reaction. Okay you’re listening to Ask Your Herob Doctor on KMUD, Galvival 91.1 FM and we’re very pleased to have Dr Ray Pete join us again and this month’s subject was the topic of bowel endotoxin. So the number if you live in the area is 9233911 or toll free number is 1-800-KMUD. So in five minutes or so we’ll be opening up the… Sorry 1-800-KMUD-RAD. Okay I had another question for you Dr. Pete. I think just very briefly then perhaps if you want to outline again what free radicals are and what foods promote or prevent the formation. Free radicals and or endotoxin? Yeah since the polyunsaturated fats are the main material that causes sort of an explosion 26:51 of free radicals once the process starts with endotoxin and nitric oxide. Simply minimizing those in the diet is a basic way to defend yourself. There have been over essentially a hundred years there have been studies showing that a fat-free diet if you give the required nutrients a fat-free diet extends lifespan and reduces cancer and other degenerative diseases, 1927 study showed that there was no spontaneous cancer in rats on a fat-free diet and that has been repeated thousands of times in different ways but there are roughly a hundred studies that show the tremendously 27:53 beneficial effects of even a short-term deficiency so-called of the polyunsaturated fats. When a rat is made deficient according to the way they define the deficiency they simply don’t feed them any polyunsaturated fats but give them purified nutrients. Those animals can stand a tremendous physical trauma that would kill a rat on a normal diet and they can be given cobalt venom and survive where a normal rat doesn’t, toxins that would produce diabetes in normal rats doesn’t hurt the so-called deficient rats. Any kind of abuse that they can think up that fatty acid deficient rats are much, 28:58 much more able to tolerate and survive without harm. So why are we so brainwashed in this day and age even to the point that these fats are called essential fatty acids? Yeah, the people, the birds who in 1929 through the 1930s were promoting that idea were working for one of the big fat businesses, lard and then vegetable shortening businesses. And when independent researchers checked their claims in the 1940s they found that what they had done was simply produce a vitamin deficiency because when an animal is not eating the polyunsaturated 29:58 fats which poison the thyroid function their metabolic rate is about 50%!h(MISSING)igher than the normal animals and if they feed them only a normal amount of vitamin and protein they become nutritionally deficient. So these researchers at the University of Texas lab in the 1940s had been working on vitamin deficiencies and they recognized that the birds had simply produced their vitamin B6 deficiency and so they gave a fatty acid deficient diet to rats and then gave them extra vitamin B6 and it cured the the syndrome. So the whole issue was settled in 1946 but in the 1950s the nutrition textbooks said that it’s a controversial topic whether they’re 31:05 essential or not because people were still promoting the idea that we need lard or vegetable shortening and then the industry went through a big change when they discovered that first they had economized on food consumption by pigs and chickens by poisoning their thyroid gland was a chemical that turned out to cause cancer in humans and so they looked for another way to poison the animal’s thyroid so it wouldn’t eat so much but would get fat and what they found was that the polyunsaturated fats just as the birds had demonstrated in 1932 suppressed the metabolic rate and that was when the feeding pigs a diet of essentially pure corn and soy for the polyunsaturated 32:11 fats took off before that they had fed them vegetable waste and and whey industrial waste which was very good for the pigs but they ate a lot of it and didn’t get fat so they weren’t good for marketing yes the the agriculture industry found that they could tremendously increase return pounds of pig per pound of food consumed and since they were at that same time the paint industry discovered how to turn petroleum into paints and plastics so they didn’t need linseed oil or safflower oil anymore and so there was this big industry soy oil and so on that wanted another market besides feeding pigs and chickens and so they convinced people 33:12 to eat their production that they couldn’t sell as paint and the story continues into 2009 yeah then after 50 years the original data which was that the vegetables caused softening of the brain and the infertility and cancer and so on that was known in the early 1940s finally that became too public that the essential fatty acids known as linoleic acid mainly everyone was catching on that those were carcinogenic and caused heart disease so about 20 or 30 years ago there was this gradual change of marketing as the fish industry was being pressured by the environmental protection agency to stop throwing their waste skins and heads and so on in in the bays or into 34:17 landfills because they were causing tremendous pollution that was when fish oil came on the market they were making fish protein out of the skin and heads to sell to Africa as a food supplement and the oil spoiled so fast they marketed it for human medical use so lesson through history that wherever there’s a waste product there’s always an agency on industry to turn it into a profitable product yeah shrimp shells are now a medical product and i’m waiting for used tires to come out rubber it’s good for you oh my gosh i don’t laugh it’ll probably happen but it’ll happen so covertly that we won’t know it for another 50 years oh my goodness i want go back briefly to that the point that you mentioned about the endotoxin or lipo polysaccharide 35:24 being broken down by the liver yeah so we know that the liver is a detoxification organ and i know that on several of our shows over the years we’ve we’ve kipped on banging the message home that you need to look after your liver because it’s the thing that looks after you very much in terms of metabolically deactivating some toxic metabolites and cleaning us helping to stay clean how do you how do you view liver health or the improvement in liver health and how would you approach that the liver has several ways to catch toxins but when it starts having to work too hard to detoxify things the brain is our second most active detoxifying organ it has very intense enzymes analogous to those that break down toxins in the liver but if the liver is spending too much 36:32 energy detoxifying it becomes unable to produce albumin albumin circulating in the blood is is one of the layers of defense when the stuff gets through into the bloodstream the high density lipo protein made in the liver increases when we’re being poisoned uh and so estrogen and alcohol increase the high density lipo protein and this is what the doctors are telling us is the good cholesterol well it is good because it’s a reaction to being poisoned so it helps protect when we’re having a bowel problem so if you have a low hgl that maybe not such a bad thing because it’s indicating you don’t have a high toxin load yeah i think that huh and the albumin circulating in the blood binds things preferentially fatty molecules 37:38 and so between the albumin and the lipo proteins our blood can hold a lot of stuff temporarily to give the liver a chance to catch up catch up as it repasses destroying them right okay because i mean i’ve heard of the albumin as being one of those factors obviously responsible for that colloidal osmotic pressure um yeah and uh when the liver is starting to be poisoned and uh estrogen and radiation can do the same thing as endotoxin uh the ability to form albumin decreases uh and so looking at the albumin in a blood test is one of the first indicators of a person’s basic resistance if it’s high their prognosis is usually good okay and if it’s uh down around three where the normal is four and a half right uh you’re going to have 38:45 to clean out the bowel i’ve seen people in just a couple weeks go from uh below three like two and a half up to uh over four just by eating fiber and and fruit juice to reduce the absorption of the endotoxin do you figure the uh given reference range to be accurate well yeah uh the um the best prognosis is in the range of 40 to 50 or four to five right and uh when it’s below four they’ve put the normal uh lower and lower as people get sicker but uh 15 or 20 years ago it was considered bad to be under four right and now it’s normal down to three point something as we all get sicker we have all right we have a caller on the line for you Dr. Pete so caller you’re on here yes Dr. Courtney i have a question for Dr. Pete but i’d first like to make a statement 39:47 is uh i’m living proof that uh this man is uh saying is is is real god sent truth uh i have closed and have had for uh probably about 20 years this diagnosis for about eight years and uh i’ve had four major surgeries at all but uh hope you and my intestines be moving and have a double ostomy and by change of diet i no longer have any crone symptoms whatsoever and it’s along the same lines that Dr. Pete is speaking about my question is Dr. Pete do common doctors understand these things and if they do why don’t they tell that to their family families that they treat sorry can i interrupt you for a second can you call her if you haven’t already turned your radio up can you please turn off we’re having quite a lot of feedback here um the average uh doctor learns um his high school courses very well and then it happens that the medical school 40:47 courses on the elementary canal and digestive physiology are really just a repeat of what the junior high and high school textbooks had in so uh doctors get a very superficial picture of nutrition and digestion i see so so possibly it is it is how i believe that they’re just trained to be uh drug pushes a lot of medical pharmaceutical companies and yeah the uh i think that’s their basic function i i’ve been running into a more and more fairly famous gastroenterologists who are barely better than than the junior high textbooks uh well i thank you very very so so much sir for for all of your your god sent wisdom and knowledge and i hope you have a long long live life sir thank you okay i think yeah there’s another caller on the line for you doctor p okay and the lights are flashing so go ahead caller hello um i have a question but i also 41:52 wanted to mention that um you had spoken last uh months about raised um heartbeat as being um preferable and um that was the first i heard of that but since then i’ve heard of that and um in another radio show so um dr p can you explain to us why the standard heart rate were taught in medical school is supposed to be between 70 and 80 beats per minute and you’ve mentioned or less or less right yeah preferably less supposedly if you have an athletic heartbeat heart rate is healthy then you are you should you have a pulse around 60 and you’re very healthy of a very healthy heart so why do people feel better when they have a pulse above 80 because the um the brain needs um oxygen and sugar and uh the just to um keep all of the systems warm and uh 42:54 respiring actively uh unless you have a very very big heart it usually takes around 80 or 90 beats per minute to pump enough uh oxygen and sugar around the tissues to keep them warm and uh over the last 30 years the normal uh temperature that doctors look for has decreased considerably for from the beginning of uh in bending thermometers normal temperature was uh around 37 centigrade 98.6 or so during the daytime Fahrenheit and uh in recent years the uh average temperature of Americans has uh decreased considerably and that means that the uh the heart rate can go slower and uh the person feels that they’re getting enough uh sugar and oxygen but they don’t really feel 44:00 as good as they should uh I’ve talked to a few people who had temporary episodes of hyperthyroidism where their heart rate went 125 for a couple of months and consistently they say they never felt so good in their life. Obviously just as an aside we since we started um since we started working with you we’ve seen so many people so many people with low temperatures and it’s always the rarity to find the person with the uh the right temperature and uh yeah it’s kind of few and far between but they certainly they certainly do react or respond rather to uh to uh the protocols that you’ve outlined there’s there’s another caller on the line for you Dr.P. Oh wait sorry uh that Corrin are you done asking questions because I know you wanted to ask a question about whether kelp and iodine rich seaweeds are good for thyroid health and I don’t know if you’re still on the line anymore. Oh well uh I’ve got in my file uh I think it’s about 80 articles on the toxic effects 45:06 of getting excess iodine and uh thyroid cancer is increasing at a tremendous rate and I think it’s uh part of it is the polyunsaturated fats but another part is a chronic lifelong overdose of iodine uh in various studies uh taking uh more than twice the essential required minimum of iodine is enough to increase the rate of uh thyroiditis and uh increase antibody attacks on the thyroid and so on. So when you sent me 20 articles detailing the thyrotoxic effects of excess iodine from sea vegetables and other sources that was just one-fifth of the articles you say you’ve seen that show this. Yeah. Right okay so we have another caller on the line and there seems to be uh seems to be a little bit of feedback going on I’m not sure if that’s uh can be managed in the studio 46:09 if that’s external. Okay caller you are? Hi yeah I had to ask you a few questions. Hi um the first one was I’m wondering if you could speak briefly about saturated fats and if they’re beneficial or not and then the other question was you mentioned staying away from the polyunsaturated fats and maybe vitamin E and a few of those that you can’t have seen that you can do to help oh oh if you can’t have this one to benefit the health so you could do co-acid for you to heal and I’ll take this one for you. Thank you. Thank you. Could you repeat the question? I couldn’t understand it. Okay well I could um here she wanted she the caller was asking what are some protective things we can do um Dr. White you’ve mentioned vitamin E oh sorry um and and also the coke uh coenzyme q10 and the lady wants to know also about 47:11 saturated fats um yeah the saturated fats are very protective but you can make make your own saturated fats if you eat enough sugar like fruits instead of uh breads. Um there are a couple groups that are curing uh cirrhosis and hepatitis with uh giving more saturated fats and excluding the unsaturated entirely so they are anti-inflammatory and therapeutic but uh you don’t necessarily have to eat the saturated fats because you can make them if you get enough sugar in the form of fruit. Okay and so the the other question was what other suggestions do you have to help reduce our bowel endotoxin load our free radical load on our bodies you’ve mentioned the coq10 the vitamin E thyroid. Well the anything 48:19 that speeds transit through the intestine and aspirin or anything anti-inflammatory the fruit juices contain some of the natural anti-inflammatory chemicals but in a pinch it can help aspirin surprisingly can act as a laxative because it suppresses nitric oxide and depends against endotoxin and and the fibers that are protective and don’t support bacterial growth are are the basic way to stimulate quick passage through the intestine and minimizing endotoxin formation. Raw carrots and boiled bamboo shoots are very good fibers because they’re germicidal as well as being able to bind the endotoxin and other 49:22 toxins. So they not only help to kill these bacteria that are producing these harmful endotoxins but they also absorb them so you can excrete them. Yeah excellent and the other herb we the herb we wanted to mention oh sorry we do have another caller on the line yeah we’ll be right back with herb. Let’s go ahead caller. Thank you um thank you doctor uh i’ve suffered from irritable bowel syndrome um all my life or ever since i was a child and then the last three years i became vegan and then in the last couple like three months i took wheat out of my diet and i used to have irritable bowel problems for at least once or twice a week and i have noticed no problems i mean very few before i took the wheat out of my diet once i became vegan but once i took the wheat out i haven’t had a problem and i would like you to address that and please um could you explain really what’s happening with irritable bowel because it’s you know they call it irritable 50:25 bowel but what is it really thank you um it basically is um the inflamed bowel and it can the same chemicals that can cause the usual paralysis that develops with aging and causes constipation um those same substances can shift over to causing intensified peristalsis leading to diarrhea but it’s all an inflammatory process that is triggered by irritants and wheat other seeds contain chemicals that the plants the the two major problems with any kind of seed especially certain grains like wheat they contain their protein in a storage form a gluten which happens to resemble a protein that our tissues make under the influence of 51:34 estrogen or stress and so if a person has some problem dealing with the control of estrogen that predisposes them to react violently to the gluten because the the same sequence of amino acids exists in our own estrogen response protein and the gluten protein but besides the the problem with the gluten seeds all are are they’re the next generation of the plant and so the plant puts its most intense toxins and defense substances into the seeds deliberately to interfere with grazing animals and such so that you can take the enzymes that are needed to digest proteins and the substance in the seed won’t affect 52:38 that type of enzyme in the plant but it affects all animal enzymes so they’re specifically designed to interfere with animal metabolism so the vegetarians forget how toxic the plants have to be because they they don’t have the ability to fight or to run and so what they use is chemical uh defense chemical weapons okay well dr p i want to be a little bit selfish and cut off any more callers at this point i know the lights are flashing and do excuse me i don’t normally do this but i do have one more specific question which relates to bowel endotoxin and bowel functioning and i know from a newsletter that you haven’t finished it’s something i know you’ve begun and i’ve managed to get a copy of it that um you’re a pretty big exponent of 53:40 cascara and cascara is a pacific northwest native tree called a ramnus persiana and the native americans have used it for centuries as an effective laxative and the main constituents are things like anthraquinones with glycosides of emodin and other aloe emodin so what do you think of how do you view constipation as a cause of morbidity and how do you view the action of cascara well all of these responses to inflammation tend to become progressive and even lead to the death of some of the nerves in the intestine and so it’s better to use any substance such as a plant uh drug rather than suffer the consequences of inflammation and it happens that cascara is has structural analogies to many of our our own substances 54:47 vitamin k and coenzyme q and progesterone have structural similarities to cascara and so what it’s doing is reinforcing our defense systems and it’s very unusual among drugs because it basically reinforces all of the good processes and doesn’t support any of the inflammatory toxic processes so it’s anti-inflammatory anti-carcinogenic helps to reduce anxiety for example increases energy production the way thyroid and progesterone do everything that our own system does it reinforces and if my newsletter is going to 55:50 talk about the history of related substances early in the century when pre-radicals were discovered uh Dr. Int. Michigan W.F. Koch began working out the implications for how to defend our cellular respiratory system from these toxins in the environment and one of the substances he worked with was the antherquinone he went to brazil and the famous brazil wood it’s red because of the antherquinone but he explored all of the quinones that he could and found that they work with vitamin e vitamin k and coenzyme q and thyroid to maintain and protect respiration excellent well i’m going to have to cut you short too i’m afraid dr because it’s uh seven fifty eight and a half 56:56 um dr ray peat can be contacted via his website on www.raypeat.org no dot com oh sorry it’s change.com so raypeat.com uh for those of you who’d like to consult further we can be reached on one eight eight eight wbm herb Monday through Friday uh thank you to all of you who listen regularly and those who tuned in this evening and thank you very much again dr peat i would love having you on this show uh and i know from the uh the wealth of people that phone up and the people that have tried to get on this evening i’m sorry that we cut short you cut you short a little um but i know that you’re very popular and you’re very much appreciated just spread the good news and we’re hoping that dr peat will come visit us in humboldt county and do some more nutrition classes so keep your ears open for that on a public service announcement look to the future folks and for those of you who have ears let them hear good night thank you good night