Vitamin D

00:00 Well, welcome to this month’s Ask Your Herb Doctor. My name is Andrew Murray and for this month Sarah won’t be with us but she will be back in December. For those of you who perhaps have never listened to the shows that run every third Friday of the month from 7 to 8pm, we’re both licensed medical herbalists who trained in England and graduated there with a degree in herbal medicine. We run a clinic in Garberville where we consult with your patients about a wide range of conditions, recommend herbs, supplements and nutritional counselling. So you’re listening to Ask Your Herb Doctor on KMU-D Garberville 91.1 FM and from 7.30 until the end of the show at 8 o’clock you’re invited to call in with any questions either related or unrelated to this month’s subject of vitamin D. The number here if you live in the area 9233911 or if you live outside the area that’s hold free numbers 1-800-568-3723 that’s 1-800-KM-UD-RAD and we can be reached toll free on 1-888-WBM-ERB 01:07 for consultations or further information Monday through Friday 9-5. Well first things first we’re very close towards the end of the pledge drive. There’s lots of people here doing all the support that it takes to run a show like this and a radio station that can’t emphasise enough is pretty unique in the States in terms of free speech radio. I know in England free speech radio was kind of maligned and pretty much kept in a very fringe area in broadcasting but not given any support other than local support and that’s what keeps this shows alive. So thank you so much to all the people that are pledging money making donations supporting the radio show keeping it on the air to make this kind of program and all the other excellent programs that KMUD brings that are just filled with 02:10 alternatives. So this is an alternative medicine show and the other alternatives are also valuable outside sources of information that you’re not going to get from the mainstream. I think in this last political campaign without being politically sited I would say that more so than ever we have seen the mainstream or lame stream media completely eradicated disingenuous and completely false. So it’s excellent to see alternative radios news sites and websites coming with the internet and the age of free information. I thought it’s a very small piece I just wanted to say about the internet and it’s the ICNN handover that was under American governance for a long time but the present administration decided to pass that off but 03:13 I’m not too sure whether this incoming administration will be able to do anything about that before a censorship carries on like it is in China for sure. Okay so this month’s talk is on vitamin D. Most people will have recognized vitamin D probably from Ricketts in the early 1900s I know in England and in many countries that are north of 37 degrees there is really various insufficient sunlight especially in the winter months to generate vitamin D and so Ricketts was a fairly common presenting condition and still is in some parts of the so we’re once again very pleased to have Dr Raymond Pete with us who’s a wealth of information and never seems to be any end to the things that he knows the things that he’s found and his insights are as always outside the box so thanks so much for joining us Dr Pete. I guess first things first would you just outline your professional and academic 04:14 background for those people who perhaps have never listened to the show and then I can get into the questioning and I’d like to run along the lines of the vitamin D subject. Basically a PhD in biology including reproductive physiology and biochemistry at the University of Oregon. I know you’ve I know you’ve got plenty more in terms of research background and I know it’s led you in very many different directions. Steroids and their production and their uses etc. I know you’re very interested in the anti-aging for one of the one of the reasons of prognolone and or progesterone in its anti-inflammatory and anti-aging effects. Now vitamin D is actually a pro hormone it’s not strictly speaking in a sense the word vitamin is it? No. So in terms of the 05:19 discovery of vitamin D and its association with rickets do you think there’s adequate vitamin D in this general populations? For preventing rickets they’re pretty pretty much all around the world there is very little rickets left but since the idea of vitamin D as a rickets preventing substance was established that really cut off thinking and research about what vitamin D really is and what it’s doing and in the 1950s there was a period when people started thinking about nutrition for themselves like Adele Davis’s books came out and the medical establishment 06:23 reacted to discourage the public from using their own therapies and for example vitamin A of the stories about how horribly toxic it was it would destroy your brain and make your skin fall off and very little evidence backing it up you can poison rats and mice giving them a million or so units of vitamin A the same there were some animal experiments with gigantic doses of vitamin D and supposedly there was a case of a a baby whose mother gave it a million or so units of vitamin D and or took it while she was pregnant and that it supposedly caused the bones to thicken so much that there was no room for the brain to develop and so the newspaper stories in the 50s were saying that vitamin D causes brain damage 07:28 and I had been reading Adele Davis in the 50s but despite that I was sort of directed away from vitamin D because there was such a taboo about anything more than two or three hundred units per day okay it’s interesting you’ve said that rickets is relatively unknown in the world I know in England and since I’ve since I’ve lived here for 15 years now but I know I kind of keep in touch with some of the news that comes from time to time that’s worth looking at and I know in England especially in northern England they were saying that rickets were starting to appear again it’s kind of a little bit off the tonight’s subject really but but the advent of fear mongering from cases of skin cancer melanoma the use of sunscreens 08:29 the inherent phobia about being in the sun all of this was actually implicated in the British medical journal as being causative for the rise in rickets it was being seen again by doctors and some people would had never seen it before it was kind of the first times for 30 and 40 year old doctors so there is there is definitely a an amount of rickets that seems to be in the populations that are at northern latitudes but in terms of the vitamin D levels measured on blood tests I know I’ve seen people with very low vitamin D and I know just like TSH as a measure of the call the body’s call for thyroid hormone has been down revised by the endocrinological association of the USA they bought it down from 4.5 to 3.5 highlighting the 09:36 fact that there are more and more people with hypothyroid type tendencies and so this figure’s been down regulated I know the levels with vitamin D the beneficial levels have been raised so that the lower limit I think was 20 nanograms per mil now they’ve raised that to 30 and a lot of people and places are advocating levels of 50 to 70 nanograms in fact for athletes I think they’ve even come up with studies that show those positive associations for 100 nanograms per mil blood levels of vitamin D what do you what do you think about that even in the absence of rickets that there is a tendency in the population to have low yeah several of the conditions that are well associated with vitamin D deficiency some of them have doubled and tripled uh in the last 20 30 years and it looks like it’s because of that fear of the sunlight 10:42 sunscreen and such I’ve talked to a few people who had 10 or below nanograms per milliliter or 15 or 20 and their condition really corresponded to how low they were like one woman in her 60s said she was so weak she could hardly walk her muscles were simply very very weak and shrunken and she had I think it was seven or eight and she per ml wow and within a week of taking just a moderate I think it was five five thousand units a day she could walk around and when you look at the the symptoms of people with 15 and she per ml 20 25 and so on you can see gradations of that weakness depression shrinking muscles of insensitivity 11:50 to insulin tendency to have high blood sugar all of all of the most common diseases of stress right and blood pressure is also associated positively isn’t it with a lower level of vitamin D um yeah everything related to aging and degenerative and stress of atrial fibrillation enlargement of the ventricle calcification of the valves degeneration of of the valves in several different ways pardoning of the arteries calcification of the coronary arteries and even calcification to the extent of what they call a heart stone a huge mass of calcium well okay and we’ll get in we’ll get into plenty of the plenty of the different conditions for which there’s been lots of peer-reviewed papers written 12:51 on uh processes that I actually wasn’t that aware of I was I think probably like most people have just associated vitamin D with calcium and phosphorus metabolism weak bones osteomalacia and you know degenerative skeletal type situations but there’s a very clear and positive link to energy production and inflammation and I know the last few shows that we’ve done with you you’ve been looking a lot at inflammation and the process is producing inflammation and the sequelae of information and how how inflammatory processes in general are extremely destructive and counterproductive to energy production when you look at the the mechanism of just the outline that calcium helps to balance or vitamin D helps to balance the relation between calcium and phosphate 13:54 and to prevent the over accumulation of phosphate and to keep up the the right level of calcium when you look at at the relation of that balance to inflammation it turns out that it’s really a serious problem in the population the amount of of phosphate relative to calcium and that’s because people aren’t eating enough dairy or green leaves leaves and and cheese and milk are really the the major good sources of of calcium and meat of nuts grains beans all of those have terrifically high phosphate contents right that the excess phosphate and the reaction of the parathyroid hormone to that high phosphate intake it’s exactly the same as a deficiency of 15:00 vitamin D so too much phosphate too little vitamin D and you get what amounts to an early stage of chronic kidney degeneration parathyroid hormone and phosphate are called urinic toxins late stage kidney disease but people are are starting that process very early when they don’t eat enough calcium and vitamin D well okay well i want to talk a little bit about the natural conversion in the skin the process by which sunlight activates the pre get cholesterol precursor and then how those metabolites are changed in the liver first and then in the kidney and how they become active and how this could play out in people with liver disease as well as kidney disease and how this could negatively impact them because they’ve automatically 16:02 um weakened the process by which this pro pro hormone is converted into the active form so you’re listening to ask Europe doctor on kmed now 91.1 FM from 7 30 until the end of the show eight o’clock you’re invited to call him if any questions Dr. Ray Pete is joining us once again and we’re discussing the widespread use of vitamin D and how important it is and i think the lack of sunlight and the phobia surrounding uh sun and cancer how this is all playing into decreasing our levels and how there aren’t that many foods that really produce uh have enough vitamin D in them to actually keep levels of vitamin D at good levels and how those levels have actually been raised uh in terms of the reference range for blood tests showing a positive association with increasing levels of vitamin D and decreasing disease so number here if you’re in the area is 93 3 9 1 1 uh if you live outside the area there’s a 800 number which is 1 800 5 6 8 3 7 2 3 or 1 800 KMUD rad so uh the lines will be open from 7 30 on so Dr. Pete i’m talking 17:08 about the conversion in the skin and again i wanted to also bring up the fact that uh i had heard and read that washing directly after sunbathing was actually counterproductive because you can wash uh the uh precursor metabolite off of the skin um don’t know how you uh how you view that as true or that’s just some bad science and then the conversion of the uh cholesterol type molecule in the skin into the uh 25 hydroxy form and how that is any further hydroxylated downstream by the kidneys to the active form um what do you think first about washing if you’re sunbathing and i think i’ve read only 20 minutes was necessary to produce peak amounts of the pro hormone so that um the body actually stopped producing uh more after about 20 minutes so it wasn’t necessary to lie out in the sun all day to get adequate vitamin D from sun exposure from UVB mainly i think that’s only when you’re um in the middle of the day at a moderate latitude 18:15 the um UVB is so low most of the year in the high latitudes that it takes a long time to get enough but um in like from 11 10 10 to 2 in the summer in high latitudes it only takes 15 or 20 minutes to get enough okay because there’s a there’s a definite um a decrease in UVB exposure with angle of the sun i mean i’m yeah so okay um given that you’re perhaps i don’t know down in san francisco um or that kind of latitude then from i know probably september through till april may you’re probably not again getting exposed to enough sunlight and if you are you probably need to be out in the sun probably for an hour or two then rather than 20 minutes um yeah and the color of your skin the natural color makes a tremendous difference and age makes a difference uh there is apparently less cholesterol metabolism and such in an old person 19:21 and just the uh degree of pigmentation uh influences the the amount of reaction you have to the ultraviolet right so that in mexico for example even women who are outside all day if they have dark skin and are only exposing their their face and hands they tend to be deficient in vitamin d even a high altitude and brilliant sunlight because i’ve read the association between our previous kind of agrarian lifestyle or at least labor based lifestyle where most people worked um for a living uh with manual labor i don’t mean people don’t work at computers or whatever these days but a manual labor they’re outdoors and more uh associated with agrarian lifestyles farming um and just being outdoors 20:22 whether it’s cutting wood or you know any other outdoor activity um those people obviously then were getting exposed to sun um but obviously with our modern lifestyles you know most people are kind of indoors and sedentary which brings its own other negative components to health but in terms of the um amount of sun that people get and using supplementation i think probably supplementation is one of the easiest way to go about getting adequate levels of vitamin d because i don’t think but do you think people get enough vitamin d from the food that they eat no that’s almost impossible yeah um if if you drink say two to four quarts of vitamin d supplemented milk right if it isn’t whole legally it has to be supplemented with vitamin d but that’s only uh i forget i don’t know what the current amount is but um it i think has been around 300 units okay something like that okay per quart well and 21:31 then i think the modern uh modern levels that are advocated now up to two thousand and a two to four thousand iu per day um so if you’re getting 300 iu from a quart of vitamin d four to five milk it’s going to take a lot of milk to reach that and it it is in a few other uh foods things like oily fish but again i know you’re not an advocate of oily fish from a poofa perspective um egg yokes is what i think we’re i think 20 iu per egg yolk so you’re not going to get a lot of vitamin d from eggs either is there any other forms of uh vitamin d rich foods oh well mushrooms mushrooms exposed to light have a lot but um interesting the um during the 40s and 50s the uh the main form of supplemental vitamin d was synthetic right by ultraviolet or radiation of fungus and uh uh the um research that changed the the popularity of that claimed that um it was responsible for 22:41 the hardening of the arteries of young people starting in the 40s and 50s and this hard sorry to interrupt but this hardening was because of calcium deposition aberrant calcium yeah which normally happens in a vitamin d deficiency but um there were publications arguing that the use of the synthetic uh vitamin d uh might have been contributing to abnormal calcium metabolism i i don’t know if that’s true but uh that came out around 1970 and uh milk uh adodides switched over to a vitamin d3 right after those articles came out so i think they were just being cautious so you said you said earlier that mushrooms exposed to light are a significant source of vitamin d do you know have any any uh figures in terms of per ounce or uh of mushrooms consumed what you what you’d get um no i don’t know it depends on the the type of mushroom and the 23:45 intensity of the ultraviolet interesting because we always think about mushrooms is growing in the dark around in the woods or something so um they they would irradiate with uvb then mushrooms at some point in our in our our history um yeah and if they gather them outside just being exposed to daylight so for a few hours is enough there have been studies using mushroom powder as a vitamin d supplement and it only took a um i think it was less than an ounce of powdered mushroom to uh make a distinct rise it actually depressed the vitamin d3 and increased the vitamin d2 wow that’s interesting i’ve never heard of that because this would be things like the common um uh field mushroom the white kind of um um the wiped agaric mushroom that’s kind of common 24:49 culinary mushroom that’d be growing in the fields button mushrooms these these would be sources yeah if they’ve been exposed at all to sunlight yeah they probably account for why many people have measurable amount of of d2 in their serum interesting now the other thing is just want to read uh go back a little bit you’ve been an advocate of mushrooms uh specifically for something else something for um producing a soup of mushrooms and having this as a uh a dietary supplement um yeah for the anti-inflammatory anti-cancer functions mainly interesting okay so i guess getting on to specific uh diseases that have been characterized with low vitamin d and how the studies have shown uh in cohorts of people that they’ve tested um those with higher initial levels of vitamin d did better in the outcomes than those with low i know we i’ve always associated 25:55 vitamin d with bones because of rickets i think most people have i don’t know how many people are actually aware of the uh cancer association with vitamin d how many people associate tb and multiple sclerosis and rheumatoid arthritis uh with vitamin d but um i’d like to bring out some of these things and um sketch your perspective on the inflammation that’s happening and how you tie in the inflammatory process uh through parathyroid hormone which i know you’ve always said is inflammatory and how you know through using thyroid hormone uh and pregnenol and being being two anti-inflammatories which quell that inflammatory cascade cascade how they tie into how you see these inflammatory disorders that i’ve mentioned rheumatoid ms etc cancers so looking at um something that i haven’t mentioned which is fibromyalgia i saw that there was a definite uh what it was a theoretical mechanism because they 26:57 haven’t tested it any further but i know the uh fibromyalgia syndrome uh where people have very tired aching muscles and they feel muscle bound and they just can’t move because their muscles are functioning i know you’d probably associate that more with hypothyroidism and low thyroid state because you’ve clearly uh spoken many times about the patella or the achilles tendon reflex and that’s a direct response of the muscle not being able to repolarize quick enough and this lag phase that happens with the twitch how do you um do you see fibromyalgia in terms of vitamin d deficiency being relative to uh energy production and and repolarization or i i think it’s um parallel almost identical to the hypothyroid condition all of the inflammations that you get with low thyroid function are structurally and functionally 27:59 similar to those you get from a vitamin d deficiency and the um thyroid stimulating hormone is an agent of those inflammatory processes actually more than the the direct effect of thyroxin which lowers tsh the tsh itself directly activates and causes tissue to release the inflammatory cytokines interleukins and so on and how parathyroid hormone does that and just by taking vitamin d or increasing your calcium intake or decreasing your phosphate relative to the calcium all of these changes in your diet will lower both tsh and parathyroid hormone and both of these hormones are directly involved in things such as mast cell activation 29:07 releasing histamine and serotonin increasing all of the cytokines tumor necrosis factor nitric oxide all of the things that promote degenerative inflammatory processes so functionally vitamin d and and thyroid are really parallel you can’t quite separate them okay and then looking at the response the immune system mounts to infection or cancer or inflammatory responses there are lots of papers published for and again this is a little bit of a divergence I know tuberculosis as a lung disease there are other lung type pathologies which were definitely seemed to improve and had or lower 30:12 morbidity associated with it with people that had higher vitamin d levels just looking at people their vitamin d level when they’re brought into hospital the higher the vitamin d when they come in the more likely they’re to go out alive right okay good point so I think it’s probably a no brainer if somebody’s in there for many different I mean how many how many different illnesses are there that you can say don’t have an inflammatory portion to them not too many right I think inflammation is one of those widespread systemic processes that happens in many pathologies and so I think just recognizing that vitamin d is implied in inflammation suppressing inflammation would make would make anybody want to supplement with vitamin d wouldn’t it yeah and HIV AIDS malaria as well as tuberculosis are very widespread conditions that are known to 31:18 increase their morbidity and mortality in proportion to how low the vitamin d is yeah I’ve read an article about a compound called catholicidine and this was a antiviral defense that again was heightened by vitamin d in the body and that lower levels produced lower levels of this other this compound and also decreased natural interferon production so these would tend to implicate viral conditions to be positively associated or the outcomes of viral conditions to be positively associated with increased vitamin d and yeah and I think the viral process is basically an energy process when when the cells are well energized they’re resistant to infection and replication of viruses right and again now you’re just saying that’s from an energetic point of view to be able to withstand 32:22 the processes that cost energy to drive a system more positively than being overwhelmed as it were yeah and I think you can see the energy process in in the brain conditions that are associated with vitamin d deficiency brain injured patients have very low vitamin d and probably the injury itself is causing it to be lost in some way I did I read that Parkinson’s was also they also implicated low levels of vitamin d in some Parkinson’s patients showing that that was a kind of interference either with dopaminergic type interference or another neural signaling interference that vitamin d positively influences and the prion diseases are probably influenced because vitamin d prevents the polymerization of the prion protein which is involved 33:25 in scraping mad cow disease Alzheimer’s disease and probably several other of the degenerative brain diseases anxiety and depression are associated with very little vitamin d yeah interesting again that’s an interesting thinking about things like from a perspective things like hypersin from st john’s walk being a classic treatment for depression and how the alchemists classified st john’s were way back before that before there was any quote unquote science although they were very very methodical and very scientific in their own right they classified is as a heating and drying in the third degree saying that it was a solar rule by the sun and so that again anxiety and depression with st john’s were used as kind of hand in hand with the sun and its energizing effects if we want to get kind of holistic about the mechanism by which that works 34:30 okay well you’re listening to ask you a doctor k me decalable 91.1 fm from now until the end of the show eight o’clock you’re invited to call in with any questions related or unrelated to this month’s subject of vitamin d its metabolism and the effects that it has on the body looks like sounds like someone’s coming into the show to do some plug-in for the pleasure so let’s bring him in now come on thank you so much so we’re stealing the airwaves go ahead we walk ahead there’s a reason a reason we’re here is because people contribute and they pay for it and they support it and it wouldn’t happen otherwise right and we need the community support and there’s a reason we have you know the why you’re on the air and why we have these talk shows is for the community to communicate with each other and it’s a really important aspect of k mud and thank you so much yeah for being here my name’s ruby voice and ether by the way and i’m and i’m rob and uh when i especially when i started listening to the station when i moved out here i 35:35 always thought of the talk shows as sort of the community sitting around the campfire you know exchanging stories and ideas and uh i don’t think that’s too far off from what actually happens so how far are we from reaching the uh oh we’re close yeah we saw that actually and we’re at 91 146 dollars so thank you so much callers for calling in to 93 3911 and we only need another 3500 uh no yeah 91,000 if you said 91 something this is 90,000 eight we’re so close so please yeah call in and uh pledge and donate and give we’re not far away so it’s very important that we keep this station fully funded i mean over and above the 90,000 95 as a goal but obviously any more over and above that is totally works towards supporting the show uh keeping the radio on the extra funds that’s right it always disappears at least as fast as it comes in that’s one of the sad realities well we um where are we at with that thousand dollar 36:38 we’re really close we um we made about a third of it but we still need a little bit more and we’re trying to reach that before eight and so um let’s call in 93 3911 and um yeah so the way a challenge works is somebody anties up a thousand dollars but we don’t get that money until other people match that challenge so like i said we have a little over 600 dollars to go until we meet the challenge so 93 3911 1800 k mud rad we’ve got a whole half hour to do it but don’t waste time folks 93 3911 let you get back to it thank you no problem yeah you’re welcome all right probably okay now i will get right back to the uh topic of vitamin d and uh its association with various pathologies here that i think some of which i hadn’t realized until i started looking at this 37:38 information earlier on today um okay so if you’re in the area and or on the internet and you have any questions again 93 3911 i know people are going to call in and pledge that’s what we want so let’s see the lights lighten up and see who’s calling there is a 800 number which is 1800 k mud rad for those people either listening to the internet or in a different state we often have people from the uh middle of the country and the east coast calling so so dr p i said at the the beginning when i started uh introducing uh this subject for this evening that i found a very interesting parallel um but i again i’m always very cautious how far down the rabbit hole to go knowing that there’s such a lot of uh misinformation especially in science i mean talk about talk about a uh reverent of revolutionary uh electoral cycle uh what we’ve seen from the mainstream media what we’ve seen uh all the stunts they’ve pulled all the lies all the cover-ups all the 38:42 conspiracy um it’s everywhere and i don’t believe that it’s not in medical journals or in especially in pharmaceutical press releases so getting to the getting to the subject of the conversion of vitamin d first in the liver and then in the kidneys before it becomes active are you aware of anything that would bypass the necessity for healthy livers and healthy kidneys in order to have adequate vitamin d if not that i think is a main stumbling block that people need to know about and hear about um i think the um low level of vitamin d and calcium is probably the cause of the sick liver and kidneys interesting go on and uh rather than being a product and so supplementing just with calcium and and vitamin d i think in many cases will 39:48 correct the whatever the liver and kidney problem is and it isn’t a matter of curing the the disease so that they can make or activate vitamin d it’s a matter of getting the vitamin d and calcium into the system and and maybe you don’t need to think about the disease of the kidney and liver is having some other mysterious cause such as a virus okay because i i read one particular abstract that um seem to show that the uh okay this was the other subject vitamin d receptors now given that i think you have said that there are many different places where the tissues in many different organs and other tissues including nerve presumably where vitamin d receptors are located so they are ubiquitous um a little bit like 40:55 the uh sites that are binding sites for various different molecules or hormones or drugs or other things that the body produces but in terms of the what they call the vitamin d receptor and its ubiquity in the body um is it reasonable um if you know but is it reasonable to increase the amount of vitamin d receptors that your genotype would express in order to overcome any short fall in the absorption of vitamin d or the uh the the pickup of vitamin d um the um receptor is um the problem of some of the stress conditions make the receptor disappear make them disappear yeah yeah i think the um getting enough calcium and vitamin d and good nutrition generally 42:02 is necessary to um make sure that you aren’t suppressing the receptors and some of the receptor repression is is done by over methylation okay and that can be uh something that your mother uh would for example was was deficient in vitamin d or calcium that sets up a methylation pattern uh in subsequent offspring that can affect their sensitivity to vitamin d by methylating the receptor or or other interacting do you know um how long lived these um uh receptors are then if you talk about a kind of transcriptional event that occurs uh in the dna to produce all these different things of one of which is of vitamin d receptor which is so important because it has such an 43:03 implication in so many different inflammatory processes and not just degenerative bone disease but down to cancers how um how long these uh vitamin d receptors last once they’ve been produced and therefore if you’re talking about the over methylation uh being negatively associated with these uh vitamin d receptors disappearing or not being produced that would be the rate at which they’re replaced and i don’t know specifically how long they last but other receptors are typically turning over very fast right so the cells can remain adaptable uh usually just two or three days and and as much of the receptor has been recycled okay we do have a caller on the air so let’s take this first caller caller you’re on the air where you from hello hi you’re on the air where you from so i’ll fit so hi um yeah i um a while back was uh had a vitamin t test and i was 44:06 kind of low and they said um uh you know to take more and then i think i was checked a while later and they said i was on the low end of normal but i still needed to up it and they suggested i take five thousand units a day so i was taking five thousand units a day but i also take a multivitamin kind of a strong multivitamin mineral i’m a little older so i want to make sure i get everything i need and um i noticed that the uh multivitamin had three thousand units in it so that meant if i was taking um both every day i’d be getting eight thousand a day is that too much well i would i would i would wonder first how uh how quantitative the uh the amount was actually in the tablet if it said three thousand how bioavailable it was over a liquid form if that was uh it was a liquid capsule that’s the five thousand uh okay yeah the liquid capsule was a five thousand but what the three thousand one that was in the multivitamin that was in a big pill yeah like so dr p eight eight 45:10 thousand are you if she got eight thousand yeah if you figure that being in a bathing suit in the sun for twenty or thirty minutes enough to just start turning pink that can make ten or fifteen thousand units oh okay five or ten thousand units is never going to be harmful so that’s not going to be harmful so if i take uh because i was starting to take a five thousand one every other day because i take the other one every day but you think i should go back to taking the five thousand every day with the uh multi yeah i’ve never heard of ten thousand a day being harmful all right and this is only eight uh did you say that you need added calcium uh for the vitamin d to work better um you need a good ratio of calcium to phosphate and uh i think it’s it’s really protective to take in well over a thousand i try to get about twenty five hundred milligrams of calcium per day i see and what are the good what are the foods that are good for that milk cheese and leafy greens 46:14 that are well cooked on the water they cook in they have to be cooked because i ate a lot of salad but those aren’t cooked so they’re you know yeah we can’t digest raw leaves so most of the calcium is is not being assimilated from salad greens so i should eat like cooked broccoli or something like that yeah yeah okay how much anything green like green beans anything that’s green has the calcium oh um one or two big servings of uh kale or um charred would give you a good part of your day’s requirement but i think the best way is to have more than a quarter day of low fat milk well i can’t possibly drink a quarter day of milk i eat a little cheese you know and uh sometimes full sour cream just for example um can i just ask you this how much 47:17 how much do you weigh i’m not going to tell you that no you should come on you don’t ask a lady who ate her weight no no it’s important i need to ask you you need to tell me i ain’t gonna tell you okay well dr p thanks thanks for your call i wanted to uh what what what does it have to do with my weight oh it has a huge amount um so if you like i’m a bit on the heavy side let’s say that yeah well it’s been very very very positive associations with a inability to absorb vitamin d uh and i’m not saying you’re obese but in obese people so the body fat has a direct uh yeah a suppressing effect on vitamin d absorption so dr p how about that you you understand that well vitamin d and calcium both have a direct suppressive effect on fat formation of the um fatty liver for example is in animal studies it’s corrected by both vitamin d and calcium so that that suppresses fat that will help you not get so fat if you eat vitamin d and calcium and the high calcium intake 48:21 by itself just with a normal amount of vitamin d is very effective at preventing overweight oh that’s good to know and what did you say would happen to the kidneys that was something bad would happen to the kidneys from not having enough calcium or not enough calcium and vitamin d not enough calcium and vitamin d or too much phosphate that the combination any of those will cause your parathyroid hormone to increase and elevated phosphate and elevated parathyroid hormone are very toxic to the kidneys uh well i actually had a um an overactive thyroid um that i had developed a few years ago i hadn’t had it before and that led to atrial fibrillation problems and i had a radioactive iodine uh to shrink the thyroid so now i take uh 88 milligrams 49:22 a day of thyroid to keep it up to the normal level so i assume i’m getting the normal level thyroid that i need uh yeah thyroid works in many ways uh similarly to vitamin d and regulates calcium and magnesium in particular well i’m taking both so i guess uh that’s a good thing okay well thank you thank you thank you for cool uh we do have another caller so let’s get this call and the lights are flashing again so let’s take this call away from what’s your question i am calling you from finland in scandinavia thank you and finland okay i was wondering if um if uh yourself for dr pete could enlighten me about uh sediment in the urine is this a good thing is it normal um any observation about sediment in the u-ring yeah okay well do you first of all do you know is this sediment is it a solid sediment or are you talking about a an amorphous kind of 50:28 sediment that’s actually part of the fluid makeup i mean is it crystalline yeah like a like a dust like cloudy if you if you let it um let’s say if you would urinate in a jar and and let it sit it would it would help it will make a cloud kind of a have you um have you ever had any investigations for any kind of kidney stones or any type of uh uh calculate that you know of or is it um i i’ve never had an issue with that um i actually uh started investigating that when i heard claims from um uh people eating mostly fruit that uh this might be a sign of good uh assimilation of or good function of the kidneys but um i’m not sure about the um the scientific claims okay dr pete what do you uh what do you think um if you have a fairly high protein intake and your 51:33 urine is on the acid side down around ph5 and you have a very high calcium intake say from the equivalent of two liters of milk per day you’ll have a lot of calcium appearing in the urine and if the urine is acidic it isn’t likely to form stones but when it stands the ph can rise and as the carbon dioxide uh evaporates and that can precipitate crystals so it other things being equal it isn’t necessarily harmful to to have a precipitation in in the urine okay did you get that very much yeah you’re welcome thank thank you for your call okay okay just quickly switching to uh urine as a kind of 52:33 urinalysis and do you do you think that people that have clear urine are uh for one of the better word healthy compared to those people that have not cloudy through pigmentation but you know uh less than see-through opaque type urines do you know if there’s any association with that because i’m sure people have wide-ranging presentations from both color and opacity i think the clarity is largely from the amount of fluid you’re drinking and uh if the urine is acidic i don’t think some cloudiness is going to hurt but there can be bad causes of cloudiness uh infection for example and i think the uh the yellow color of urine is considered to indicate uh cell turnover so sometimes the the morning urine will be yellow and the afternoon urine clear because during the night uh when the high stress 53:41 hormones a lot of cells are breaking down and the uh the fragments of the nucleic acids turning over i think can produce some of the yellow pigment okay well i’m i’m afraid that is all we’ve got time for because we’re coming up close to two minutes to eight thank you very much for your time dr. peat um i wanted to mention that the clotho protein that we talked about a few months right okay is the anti-aging protein yeah um it’s very similar to vitamin d in some of its functions that vitamin d deficiency produces the degenerative changes that a mutation or deficiency of the clotho protein can produce interesting well i really wanted to talk more to you about um the vitamin d receptor um and how that could be enhanced because i think vitamin d uh is just the tip of the iceberg in terms of the process of inflammation and all the 54:44 diseases associated with maybe next month we can pick up uh just the last part of what i wanted to look at with vitamin d and maybe bring the vitamin d receptor into more light and help people understand how important vitamin d is to get especially now we’re going into the darker times of the year so thanks so much for your time dr. peat the calcium metabolism and sugar oxidation is another subject all right excellent good i’ve got some notes here thanks thanks very much okay thank you okay so for those people that have listened to the show this evening uh thanks for either calling in or listening i can only hope that there are lots of people out there who listened and didn’t call but i would also stress the point that this is a funded radio station uh we do need your financial support so hopefully the uh phone will ring off the hook once eight o’clock comes around here and people will start pledging uh for those of you who’ve listened to the show uh thanks so much the truth is out there there’s lots of information on the internet uh don’t believe the media the media is dying uh in fact the media is 55:47 virtually dead i think it’s got a six percent trust rating at this point in time so uh thanks for listening and until december uh next month good night